Endocrine Abstracts

Introduction: Ectopic Cushing’s syndrome (ECS) is a condition caused by an ACTH-secreting tumor outside the pituitary or adrenal glands. Most cases are caused by neuroendocrine tumors of the lung, pancreas, thymus or medullary carcinoma of the thyroid. Small-cell carcinomas of the lung are probably the most common cause of biochemical hypercortisolism. About 15% of Cushing’s syndrome cases are due to ECS.Case description: A 27-year-old male pat...

Introduction: Cushing’s disease (CD) accounts for approximately 80% of cases of Cushing’s syndrome. Almost all patients with CD have a pituitary adenoma. The tumors are usually microadenomas, only approximately 5 to 10 percent are macroadenomas. Pituitary adenomas arise from epithelial pituitary cells and account for 10–15% of all intracranial tumors. Pituitary imaging is important in confirming the diagnosis of pituitary macroadenoma and also for determining th...